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| Catalog Code: | NB100-78259 |
| Product Name: | MCM3 Antibody |
| Product Description: | Rabbit Polyclonal anti-MCM3 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Peptide-KLH (SDTEEEMPQVHTPKTAD) |
| Cross Reactivity: | Mouse, Human. |
| Packaging: | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | The MCM3 protein (minichromosome maintenance protein 3) is a 110 kD DNA-dependent ATPase containing a nuclear localization sequence. The MCM3 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM3 is constitutively expressed and can be modified by acetylation. Acetylation of MCM3 inhibits the initiation of DNA replication. MCM3 has been reported to interact with the MCM5 (CDC46) and MCM3AP proteins. The Poly6023 antibody recognizes both human and mouse MCM3 and has been shown to be useful for Western blotting. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| Application Summary: | Western Blot |
| Species Summary: | Mu, Hu |
| Alternate Names: | anti-Minichromosome maintenance protein 3 antibody |
| Package Size: | 0.2 ml |
| General References: | 1. Hu, B., et al., 1993. Nucleic Acids Res. 21:5289. 2. Ishimi, Y. 1997. J. Biol. Chem. 272:24508. 3. Ishimi, Y., et al., 2003. J. Biol. Chem. 278:24644. |
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