| CatalogCode: | NB100-78258 |
| ProductName: | MCM2 Antibody |
| Product Description: | Rabbit Polyclonal anti-MCM2 |
| Clonality: | Polyclonal |
| Immunogen: | Recombinant (partial), C-terminal |
| CrossReactivity: | Mouse, Human. |
| Packaging: | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Nuclear |
| Background: | The MCM2 protein (minichromosome maintenance protein 2) is a 120 kD member of the MCM family that forms a heterotetramer with other family members. This nuclear protein functions in eukaryotic genome replication. MCM2 forms a complex with MCM4, MCM6, and MCM7. MCM2 regulates the helicase activity of the pre-replication complex and is involved in the formation of replication forks. MCM2 is regulated by protein kinases Cdc2 and Cdc7 and can be modified by phosphorylation. The Poly6022 antibody recognizes the C-terminal region of both human and mouse MCM2 and has been shown to be useful for Western blotting. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | 285 |
| AppSummary: | IF, WB |
| SpeciesSummary: | Mu, Hu |
| ALTnames: | anti-Minichromosome maintenance protein 2 antibody, anti-Cdc19 antibody |
| ProteinTarget: | MCM2 |
| PackageSize: | 0.2 ml |
| GeneralRef: | 1. Todorov, I., et al., 1994. J. Cell. Sci. 107:253. 2. Fujita, M., et al., 1998. J. Biol. Chem. 273:17095. 3. Kodani, I., et al., 2001. Pathobiology 69:150. 4. Yabuta, N., et al., 2003. Genes Cells 8:413. |
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