| CatalogCode: | | NB100-78220 |
| ProductName: | | IL-8 Antibody |
| Product Description: | | Mouse Monoclonal anti-IL-8 (JK8-1) |
| Clone: | | JK8-1 |
| Clonality: | | Monoclonal |
| Immunogen: | | Recombinant human IL-8 |
| CrossReactivity: | | Human, 72aa and 77aa isoforms.. |
| Packaging: | | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-6 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-8 recombinant protein ranging from 2000 to 15 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.Important Note: DO NOT use FBS (Fetal Bovine Serum) in any solutions in this ELISA. We recommend 1% BSA for blocking and dilutions in this assay. |
| Control: | | Neutrophils, basophils, lymphocytes |
| Background: | | IL-8, also known as neutrophil chemotactic factor, neutrophil activating protein, and monocyte-derived neutrophil chemotactic factor, is a member of the alpha (C-X-C) subfamily of chemokines called CXCL8. In response to proinflammatory stimuli, IL-8 is produced by monocytes, macrophages, T cells, neutrophils, and fibroblasts. IL-8 promotes neutrophil chemotaxis and degranulation. The 72 amino acid IL-8 is the predominant form secreted by monocytes and lymphocytes. The JK8-1 antibody reacts with the 72 aa and 77 aa forms of human interleukin-8 (IL-8). The JK8-1 antibody can neutralize the bioactivity of natural or recombinant IL-8. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG1, kappa |
| Host_Name: | | Mouse |
| Buffer: | | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | | 295 |
| AppSummary: | | ELISA, ICC, FACS, IP |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-Interleukin-8 antibody, anti-Neutrophil activating protein-1 antibody, anti-Monocyte-derived neutrophil chemotactic factor (MDNCF) antibody, anti-Neutrophil activating factor (NAF) antibody, anti-Leukocyte adhesion inhibitor (LAI) antibody, anti-Granulocyte chemotactic protein (GCP) antibody, anti-CXCL8 antibody |
| ProteinTarget: | | IL-8 |
| PackageSize: | | 0.5 mg |
| GeneralRef: | | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Baggiolini, M., et al., 1994. Adv. Immunol. 55:97. 3. Schr oumlder, J., et al., 1992. Immunology Ser. 57:387. |
| more information: | | company product webpage |
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