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| Catalog Code: | NB100-78218 |
| Product Name: | IL-1 beta Antibody |
| Product Description: | Mouse Monoclonal anti-IL-1 beta (JK1B-2), conjugated to Biotin |
| Clone: | JK1B-2 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Immunogen: | Recombinant human IL-1 beta |
| Cross Reactivity: | Human. |
| Packaging: | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 1-4 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of human IL-1 beta protein ranging from 250 to 2 pg/ml are recommended for each ELISA plate. For use as an ELISPOT detection antibody, a concentration range of 2-8 mug/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | IL-1 refers to two proteins, IL-1 alpha and IL-1 beta which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1 beta is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. The JK1B-2 antibody reacts with human interleukin-1 beta (IL-1 beta) and baboon IL-1 beta. The JK1B-2 antibody does not recognize mouse IL-1 beta or human IL-1 alpha or other cytokines. The JK1B-2 antibody can neutralize the bioactivity of natural or recombinant IL-1 beta. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2b, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | ELISA |
| Species Summary: | Hu |
| Alternate Names: | anti-Interleukin-1 beta antibody, anti-Catabolin antibody, anti-Hematopoietin-1 (H1) antibody, anti-IFN beta antibody, anti-Interleukin-beta antibody, anti-Osteoclast activating factor (OAF)-1beta antibody, anti-IL1beta antibody |
| Package Size: | 0.5 mg |
| Conjugate: | Biotin |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone pair: JK1B-1 - JK1B-2 For Sandwich ELISA pair this antibody with: NB100-78216 |
| General References: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Bomford, R., et al., Eds. 1989. Interleukin-1, inflammation and disease. Elsevier, New York. 3. Brazel, D., et al., 1991. Biotechnol. Ther. 2:241. |
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