| CatalogCode: | NB100-78197 |
| ProductName: | MCP-1 Antibody |
| Product Description: | Hamster Monoclonal anti-MCP-1 (2H5), conjugated to Biotin |
| Clone: | 2H5 |
| Clonality: | Monoclonal |
| Immunogen: | CHO-expressed, recombinant mouse MCP-1 |
| CrossReactivity: | Moue, Rat, Human. |
| Packaging: | 0.5 mg Immunogen affinity purified Hamster antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 1-4 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of MCP-1 recombinant protein ranging from 1000 to 8 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Monocytes, basophils, T cells, NK cells, immature dendritic cells |
| Background: | Monocyte chemotactic protein-1 (MCP-1) also known as monocyte chemotactic and activating factor (MCAF) was identified based on its ability to chemoattract monocytes. Subsequently, MCP-1 has also been found to regulate adhesion molecule expression and cytokine production in monocytes. MCP-1 is identical to the product of the JE gene, a PDGF inducible gene. MCP-1 is a member of the beta (C-C) chemokine subfamily, known as CCL2. The 2H5 antibody reacts with mouse, rat, and human MCP-1. The 2H5 antibody can neutralize the bioactivity of natural or recombinant MCP-1. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Hamster |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | 325 |
| AppSummary: | ELISA, ICC, FACS |
| SpeciesSummary: | Mu, Rt, Hu |
| ALTnames: | anti-Monocyte chemoattractant protein-1 antibody, anti-Monocyte chemoattractant and activating factor (MCAF) antibody, anti-JE antibody, anti-Small inducible cytokine A2 (SCYA2) antibody, anti-HC-11 antibody, anti-P6 antibody, anti-Smooth muscle cell chemotactic factor (SMC-CF) antibody, anti-CCL2 antibody |
| ProteinTarget: | MCP-1 |
| PackageSize: | 0.5 mg |
| Conjugate: | Biotin |
| GeneralRef: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Bischoff, S., et al., 1992. J. Exp. Med. 175:1271. 3. Charo, I., et al., 199 |
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