| CatalogCode: | | NB100-78187 |
| ProductName: | | GM-CSF Antibody |
| Product Description: | | Rat Monoclonal anti-GM-CSF (MP1-22E9) |
| Clone: | | MP1-22E9 |
| Clonality: | | Monoclonal |
| Immunogen: | | Yeast-expressed, recombinant mouse GM-CSF. |
| CrossReactivity: | | Mouse. |
| Packaging: | | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, the antibody should be titrated between 1-4 microgram/ml to determine optimal concentration. To obtain a linear standard curve, serial dilutions of GM-CSF recombinant protein ranging from 2000 to 15 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | Granulocyte/macrophage/erythroid/megakaryocytic progenitors, myeloblasts, monoblasts |
| Background: | | GM-CSF is a hematopoietic factor that is produced by T cells, macrophages, fibroblasts and endothelial cells. This multifunctional cytokine stimulates progenitor cells of neutrophils, eosinophils and macrophages. GM-CSF is also a differentiation and activating factor for granulocytic and monocytic cells. The MP1-22E9 antibody reacts with mouse granulocyte/macrophage-colony stimulating factor (GM-CSF). The MP1-22E9 antibody can neutralize the bioactivity of natural or recombinant GM-CSF. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG2a, kappa |
| Host_Name: | | Rat |
| Buffer: | | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | | 285 |
| AppSummary: | | ELISA, ICC, FACS, IHC |
| SpeciesSummary: | | Mu |
| ALTnames: | | anti-Granulocyte/macrophage-colony stimulating factor antibody, anti-CSF-alpha; antibody, anti-Pluripoietin-α antibody, anti-Eosinophil colony stimulating factor (Eo-CSF) antibody, anti-Burst promoting activity (BPA) antibody, anti-GM CSF antibody |
| ProteinTarget: | | GM-CSF |
| PackageSize: | | 0.5 mg |
| GeneralRef: | | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Demetri, G., et al., 1991. Blood 78:2791. 3. Fan, D., et al., 1991. In vivo 5:571. |
| more information: | | company product webpage |
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