| CatalogCode: | NB100-78186 |
| ProductName: | IL-12 Antibody |
| Product Description: | Rat Monoclonal anti-IL-12 (C17.8), conjugated to Biotin |
| Clone: | C17.8 |
| Clonality: | Monoclonal |
| Immunogen: | CHO expressed, recombinant mouse IL-12 p70 |
| CrossReactivity: | Mouse, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40). |
| Packaging: | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 0.25-1.0 mug/ml is recommended. For use as an ELISPOT detection antibody, a concentration range of 0.5-2.0 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-12 recombinant protein ranging from 250 to 2 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | T cells, NK cells |
| Background: | The C17.8 antibody reacts with mouse IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C17.8 antibody can neutralize the bioactivity of natural or recombinant IL-12. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2a, kappa |
| Host_Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | 325 |
| AppSummary: | ELISA, ICC, FACS |
| SpeciesSummary: | Mu |
| ALTnames: | anti-Interleukin-12 p40 antibody, anti-Interleukin-23 p40 antibody, anti-Cytotoxic lymphocyte maturation factor (CLMF) antibody, anti-Natural killer cell stimulatory factor (NKSF) antibody, anti-CTL maturation factor (TcMF) antibody, anti-T-cell stimulating factor (TSF) antibody |
| ProteinTarget: | IL-12 |
| PackageSize: | 0.5 mg |
| Conjugate: | Biotin |
| GeneralRef: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Quesniaux, V. 1992. Research Immunol. 143:385. 3. Trinchieri, G., et al., 1992 Prog. Growth Factor Res. 4:355. |
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