| CatalogCode: | | NB100-78154 |
| ProductName: | | GM-CSF Antibody |
| Product Description: | | Rat Monoclonal anti-GM-CSF (BVD2-21C11), conjugated to Biotin |
| Clone: | | BVD2-21C11 |
| Clonality: | | Monoclonal |
| Immunogen: | | E. coli - expressed, recombinant human GM-CSF |
| CrossReactivity: | | Human, Expected Cross-Reactivity based on immunogen sequence: Rhesus. |
| Packaging: | | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | | Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 0.25-1.0 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of human GM-CSF protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | Granulocyte/macrophage/erythroid/megakaryocytic progenitors, myeloblasts, monoblasts |
| Background: | | Granulocyte/macrophage - colony stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T cells, B cells, mast cells, macrophages, fibroblasts and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte and eosinophil progenitors. The BVD2-21C11 antibody reacts with human granulocyte/macrophage-colony stimulating factor (GM-CSF). The BVD2-21C11 antibody can neutralize the bioactivity of natural or recombinant GM-CSF. |
| Storage: | | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG2a, kappa |
| Host_Name: | | Rat |
| Buffer: | | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | | 325 |
| AppSummary: | | ELISA, ICC, FACS |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-Granulocyte-Colony Stimulating Factor antibody, anti-CSF-beta antibody, anti-Pluripoietin antibody, anti-Granulocytic neutrophil colony stimulating activity (G-CSA) antibody, anti-Macrophage-granulocyte inducer-2 (MGI-2) antibody |
| ProteinTarget: | | GM-CSF |
| PackageSize: | | 0.5 mg |
| Conjugate: | | Biotin |
| GeneralRef: | | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Demetri, G., et al., 1991. Blood 78:2791. 3. Fan, D., et al., 1991. In vivo 5:571. |
| more information: | | company product webpage |
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