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| Catalog Code: | NB100-78151 |
| Product Name: | G-CSF Antibody |
| Product Description: | Rat Monoclonal anti-G-CSF (BVD13-3A5) |
| Clone: | BVD13-3A5 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | E. coli-expressed, recombinant human G-CSF |
| Cross Reactivity: | Human. |
| Packaging: | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 1-4 mug/ml is recommended. IMmunohistochemistry-frozen/paraffin. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | Granulocyte - colony stimulating factor (G-CSF) is a potent stimulator of bone marrow cells especially those of neutrophilic granulocyte lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. G-CSF is produced primarily by monocytes and macrophages upon activation by endotoxin, TNF-alpha or IFN-gamma. The BVD13-3A5 antibody reacts with human granulocyte-colony stimulating factor (G-CSF). The BVD13-3A5 antibody can neutralize the bioactivity of natural or recombinant G-CSF. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | ELISA, immunohistochemistry |
| Species Summary: | Hu |
| Alternate Names: | anti-Granulocyte-Colony Stimulating Factor antibody, anti-CSF-beta antibody, anti-Pluripoietin antibody, anti-Granulocytic neutrophil colony stimulating activity (G-CSA) antibody, anti-Macrophage-granulocyte inducer-2 (MGI-2) antibody |
| Package Size: | 0.5 mg |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone pair: BVD13-3A5 - BVD11-37G10 For Sandwich ELISA pair this antibody with: NB100-78209 |
| General References: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Demetri, G., et al., 1991. Blood 78:2791. 3. Moore, M. 1991. Annu. Rev. Immunol. 9:159. |
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