| CatalogCode: | NB100-78142 |
| ProductName: | IL-7 Antibody |
| Product Description: | Rat Monoclonal anti-IL-7 (BVD10-40F6) |
| Clone: | BVD10-40F6 |
| Clonality: | Monoclonal |
| Immunogen: | E. coli - expressed, recombinant human IL-7 |
| CrossReactivity: | Human. |
| Packaging: | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-6 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-7 recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Progenitor B and T cells; CD4-CD8- thymocytes; megakaryocytes |
| Background: | IL-7 is a potent lymphoid cell growth factor which promotes the proliferation of pre-B cells, thymocytes, T cell progenitors, and mature T cells. IL-7 induces formation of LAK cells and CTLs, and can stimulate tumoricidal activity of monocytes and macrophages. IL-7 can induce upregulation of proinflammatory cytokines in myeloid cells. IL-7 is expressed by stromal cells. The BVD10-40F6 antibody can neutralize the bioactivity of natural or recombinant IL-7. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host_Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | 325 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Interleukin-7 antibody, anti-Lymphopoietin-1 (LP-1) antibody, anti-Pre-B cell growth factor antibody, anti-Thymocyte growth factor antibody |
| ProteinTarget: | IL-7 |
| PackageSize: | 0.5 mg |
| GeneralRef: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Park, L., et al., 1992. Adv. Exp. Med. Biol. 323 125. 3. Melchers, F., et al., 1992. Adv. Exp. Med. Biol. 323 111. |
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