| CatalogCode: | NB100-78136 |
| ProductName: | IL-5 Antibody |
| Product Description: | Rat Monoclonal anti-IL-5 (JES1-5A10) |
| Clone: | JES1-5A10 |
| Clonality: | Monoclonal |
| Immunogen: | COS-expressed, recombinant human IL-5 |
| CrossReactivity: | Human, Expected Cross-Reactivity based on immunogen sequence: Cynomolgus, Rhesus. |
| Packaging: | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 1-4 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-5 recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Eosinophils |
| Background: | IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. The JES1-39D10 antibody can neutralize the bioactivity of natural or recombinant IL-5. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2a, kappa |
| Host_Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | 285 |
| AppSummary: | ELISA, ICC, FACS, IHC, WB |
| SpeciesSummary: | Hu, Mk |
| ALTnames: | anti-Interleukin-5 antibody, anti-Eosinophil differentiation factor (EDF) antibody, anti-Eosinophil colony stimulating factor (Eo-CSF) antibody, anti-B cell growth factor-2 (BCGF-2) antibody, anti-B cell differentiation factor for IgM (BCDF-m) antibody, anti-IgA enhancing factor (IgA-EF) antibody, anti-T cell replacing factor-1 (TRF-1) antibody |
| ProteinTarget: | IL-5 |
| PackageSize: | 0.5 mg |
| GeneralRef: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Takatsu, K., et al., 1988. Immunol. Rev. 102:107. 3. Takatsu, K. 1992. Curr. Opin. Immunol. 4:299. |
order or
more information: | company product webpage |
| request information: |
|
|