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| Catalog Code: | NB100-78124 |
| Product Name: | IL-2 Antibody |
| Product Description: | Rat Monoclonal anti-IL-2 (MQ1-17H12) |
| Clone: | MQ1-17H12 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | E. coli - expressed recombinant human IL-2 |
| Cross Reactivity: | Human, Expected Cross-Reactivity based on immunogen sequence: Chimpanzee, Baboon, Cynomolgus, Rhesus. |
| Packaging: | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-6 mug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-2 recombinant protein ranging from 2000 to 15 pg/ml are recommended for each ELISA plate. Immunohistochemistry. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells promoting proliferation and maturation. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2). The MQ1-17H12 antibody can neutralize the bioactivity of natural or recombinant IL-2. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2a, kappa |
| Host Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | ELISA, Immunocytochemistry, flow cytometry / FACS analysis, immunohistochemistry, immunoprecipitation |
| Species Summary: | Hu, Bb, Mk |
| Alternate Names: | anti-Interleukin-2 antibody, anti-T cell growth factor (TCGF) antibody, anti-Eosinophil differentiation factor (EDF) antibody, anti-Killer cell helper factor (KHF) antibody, anti-Macrophage-activating factor for cytotoxicity I (MAF-C I) antibody, anti-Thymocyte differentiation factor (TDF) antibody |
| Package Size: | 0.5 mg |
| General References: | 1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Taniguchi, T., et al., 1993. Cell 73:5. 3. Nistico, G. 1993. Prog. Neurobiol. 40:463. |
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