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| Catalog Code: | NB100-78031 |
| Product Name: | CD182 Antibody |
| Product Description: | Mouse Monoclonal anti-CD182 (5E8/CXCR2), conjugated to FITC |
| Clone: | 5E8/CXCR2 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Cross Reactivity: | Human. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CXCR2 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor B (IL-8RB), CD182, and CD128b. It is a CXC chemokine receptor belongs to G protein-coupled receptor (CPCR) family. CXCR2 is expressed as homodimer or heterodimer with CXCR1 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. CXCR2 mediates nurophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO- alpha, beta, gamma (CXCL1, CXCL2, CXCL3). |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-CD182 antibody, anti-CXCR2 antibody, anti-CD128b antibody, anti-IL-8RB antibody, anti-Type II IL-8 receptor antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
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more information: | company product webpage |
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