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| Catalog Code: | NB100-78028 |
| Product Name: | CD181 Antibody |
| Product Description: | Mouse Monoclonal anti-CD181 (8F1/CXCR1), conjugated to Biotin |
| Clone: | 8F1/CXCR1 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor belongs to G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower that of CXCR2. CXCR1 mediates nurophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO- alpha(CXCL1). |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2b, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-CD181 antibody, anti-CXCR1 antibody, anti-CDw128 antibody, anti-CD128a antibody, anti-IL-8RA antibody, anti-Type I IL-8 receptor antibody |
| Package Size: | 0.1 mg |
| Conjugate: | Biotin |
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