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| Catalog Code: | NB100-78006 |
| Product Name: | CD30 Antibody |
| Product Description: | Mouse Monoclonal anti-CD30 (MEM-268), conjugated to FITC |
| Clone: | MEM-268 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Recombinant human CD30 boosted with THP-1 cell lin |
| Cross Reactivity: | Human. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD30, also known as Ki-1 antigen, lymphoid activation antigen CD30, and tumor necrosis factor receptor superfamily member 8 is a type I transmembrane receptor that contains four TNF receptor domains with an approximate molecular weight of 64 kD. CD30 is highly expressed on Hodgkins and Reed-Sternberg cells as well as activated, but not resting, T and B cells. CD30 has been shown to interact with a number of proteins including TRAF1, TRAF2, TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, and CD30 ligand (CD153). Signaling through CD30 is thought to limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-ber-H2 antibody, anti-Ki-1 antibody, anti-TNFRSF8 antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
| General References: | 1. Durkop, H., et al. 1992. Cell 68:421.2. Aizawa, S., et al. 1997. J. Biol. Chem. 272:2042.3. Stein, H., et al. 1982. Int. J. Cancer 30:445. |
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