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| Catalog Code: | NB100-77970 |
| Product Name: | CD108 Antibody |
| Product Description: | Mouse Monoclonal anti-CD108 (MEM-150) |
| Clone: | MEM-150 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | HPB-ALL T cell line |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD108 is an 80 kD GPI-linked membrane-bound semaphorin, also known as JMH blood group antigen, semaphorin 7A, H-SEMA, and SEMAL. It contains an Ig-like domain and is expressed at low levels on erythrocytes and lymphocytes. The expression of CD108 on lymphocytes is upregulated upon activation. CD108 is a guidance protein known for immunomodulatory effects that has been shown to enhance central and peripheral axon growth. CD108 interacts with plexin C1. The MEM-150 antibody has been shown to be useful for flow cytometry, Western blotting, and immunoprecipitation. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgM, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis, immunoprecipitation, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-JMH blood group antigen antibody, anti-semaphorin 7A antibody, anti-H-SEMA antibody, anti-SEMAL antibody |
| Package Size: | 0.1 mg |
| General References: | 1. Leukocyte Typing V. Schlossman, S., et al., (eds), Oxford University Press (1995)2. Pasterkamp, R. J., et al., 2003. Nature 424:398.3. Xu, X., et al., 1998. J. Biol. Chem. 273:22428. |
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