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| Catalog Code: | NB100-77969 |
| Product Name: | CD98 Antibody |
| Product Description: | Mouse Monoclonal anti-CD98 (MEM-108), conjugated to FITC |
| Clone: | MEM-108 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Burkitt's lymphoma cell line Raji |
| Cross Reactivity: | Human. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD98 is a 125 kD disulfide-linked heterodimer protein also known as 4F2 and FRP-1. It is broadly expressed on activated and transformed cells (hematopoietic and non-hematopoietic), and at low levels on quiescent cells. CD98 has been characterized as a potential amino acid transporter (neutral and dibasic amino acids) that is involved in lymphocyte activation and integrin signaling. CD98 is composed of a light chain (45 kD) and a heavy chain (80 kD). Studies with knock-out mice indicate that the CD98 heavy chain is involved in integrin-dependent cell spreading and protection against anchorage deprivation-induced apoptosis. The MEM-108 antibody is useful for flow cytometry and immunoprecipitation. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-4F2 antibody, anti-FRP-1 antibody, anti-RL-388 antibody, anti-FRP1 antibody, anti-RL388 antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
| General References: | 1. Leukocyte Typing VI. Kishimoto, T., et al., (Eds.) Garland Publishing Inc. (1997)2. Bron, C., et al., 1986. J. Immunol. 137:397.3. Lumadue, J.A., et al., 1987. Proc. Natl. Acad. Sci. 84:9204. |
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