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| Catalog Code: | NB100-77965 |
| Product Name: | CD48 Antibody |
| Product Description: | Mouse Monoclonal anti-CD48 (MEM-102), conjugated to FITC |
| Clone: | MEM-102 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Raji cell line (Burkitt's lymphoma) |
| Cross Reactivity: | Human, Expected Cross-Reactivity based on immunogen sequence: Rhesus. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn. The MEM-102 antibody is useful for flow cytometry, Western blotting, immunoprecipitation, and immunohistochemistry. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-Blast-1 antibody, anti-HuLy-m3 antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
| General References: | 1. Fisher, R. C., and Thorley-Lawson, D. A. 1991. Mol. Cell. Biol. 11:1614.2. Korinek, V., et al., 1991. Immunogenetics 33:108.3. Leukocyte Typing IV. Knapp, W., et al., (Eds), Oxford University Press (1989) |
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