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| Catalog Code: | NB100-77900 |
| Product Name: | CD154 Antibody |
| Product Description: | Mouse Monoclonal anti-CD154 (24-31), conjugated to Biotin |
| Clone: | 24-31 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Cross Reactivity: | Human, Expected Cross-Reactivity based on immunogen sequence: Cynomolgus. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 2 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood . It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2 |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-CD40L antibody, anti-gp39 antibody, anti-TRAP antibody, anti-T-BAM antibody, anti-TBAM antibody, anti-TNFSF5 antibody |
| Package Size: | 0.1 mg |
| Preservative: | Sodium Azide |
| Conjugate: | Biotin |
| General References: | 1. Najafian, N., et al., 2003. Expert Opin. Biol. Ther. 3:227. 2. Racke, M., et al., 2002. Expert Opin. Ther. Targets. 6:275. 3. Ford, G., et al., 1999. J. Immunol. 162:4037. |
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