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| Catalog Code: | NB100-77899 |
| Product Name: | CD154 Antibody |
| Product Description: | Mouse Monoclonal anti-CD154 (24-31), conjugated to FITC |
| Clone: | 24-31 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Cross Reactivity: | Human, Expected Cross-Reactivity based on immunogen sequence: Cynomolgus. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-CD40L antibody, anti-gp39 antibody, anti-TRAP antibody, anti-T-BAM antibody, anti-TBAM antibody, anti-TNFSF5 antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
| General References: | 1. Najafian, N., et al., 2003. Expert Opin. Biol. Ther. 3:227. 2. Racke, M., et al., 2002. Expert Opin. Ther. Targets. 6:275. 3. Ford, G., et al., 1999. J. Immunol. 162:4037. |
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