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| Catalog Code: | NB100-77893 |
| Product Name: | CD50 Antibody |
| Product Description: | Mouse Monoclonal anti-CD50 (MEM-171), conjugated to FITC |
| Clone: | MEM-171 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Human granulocytes |
| Cross Reactivity: | Human. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3 (ICAM-3). It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 is a member of the Ig superfamily. It provides costimulatory signal for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, alphaL/ beta2) integrin. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-ICAM-3 antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
| General References: | 1. Valent, P., et al., 2001. Immunol. Rev. 179:74. |
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more information: | company product webpage |