| request information: |
|
| Catalog Code: | NB100-77892 |
| Product Name: | CD50 Antibody |
| Product Description: | Mouse Monoclonal anti-CD50 (MEM-171) |
| Clone: | MEM-171 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Human granulocytes |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3 (ICAM-3). It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 is a member of the Ig superfamily. It provides costimulatory signal for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, alphaL/ beta2) integrin. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis, immunoprecipitation |
| Species Summary: | Hu |
| Alternate Names: | anti-ICAM-3 antibody |
| Package Size: | 0.1 mg |
| General References: | 1. Valent, P., et al., 2001. Immunol. Rev. 179:74. |
order or
more information: | company product webpage |