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| Catalog Code: | NB100-77891 |
| Product Name: | CD7 Antibody |
| Product Description: | Mouse Monoclonal anti-CD7 (MEM-186), conjugated to FITC |
| Clone: | MEM-186 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | KG-1 human acute myeloid leukemia cell line |
| Cross Reactivity: | Human. |
| Packaging: | 100 tests Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microliter per million cells or 20 microliter per 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-gp40 antibody |
| Package Size: | 100 tests |
| Conjugate: | FITC |
| General References: | 1. Barclay, N., et al., 1993. The Leucocyte Antigen FactsBook. Academic Press Inc. San Diego. 2. Stillwell, R., et al., 2001. Immunol. Res. 24:31. 3. Rabinowich, H., et al., 199 |
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