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| Catalog Code: | NB100-77889 |
| Product Name: | CD10 Antibody |
| Product Description: | Mouse Monoclonal anti-CD10 (MEM-78) |
| Clone: | MEM-78 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Pre-B cell line NALM-6 |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at: 1.0 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood. For Western blotting, the suggested use of this reagent is: 4 microgram/ml. Immunohistochemistry-frozen sections. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis , immunoprecipitation , Western Blot , Immunohistochemistry-Frozen |
| Species Summary: | Hu |
| Alternate Names: | anti-CALLA antibody, anti-Enkephalinase antibody, anti-Neutral endopeptidase antibody, anti-Neprilysin antibody |
| Package Size: | 0.1 mg |
| General References: | 1. Shipp, M., et al., 1993. Blood 82:1052. 2. Lu, B., et al., 1995. J. Exp. Med. 181:2271. |
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