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| Catalog Code: | NB100-77887 |
| Product Name: | CD137 Antibody |
| Product Description: | Mouse Monoclonal anti-CD137 (4B4-1) |
| Clone: | 4B4-1 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Ectodomain of recombinant human 4-1BB fusion protein |
| Cross Reactivity: | Human, Expected Cross-Reactivity based on immunogen sequence: Chimpanzee, Baboon, Cynomolgus, Rhesus. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CDw137 is a 39 kD transmembrane protein, also known as 4-1BB. It is expressed on activated T cells. CDw137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CDw137 appears to be important for T cell proliferation and survival and induces monocyte activation through its interaction with 4-1BB ligand. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | ELISA, flow cytometry / FACS analysis, immunoprecipitation |
| Species Summary: | Hu, Bb, Mk |
| Alternate Names: | anti-4-1BB antibody, anti-ILA antibody, anti-TNFRSF9 antibody, anti-CDw137 antibody |
| Package Size: | 0.1 mg |
| General References: | 1. Gruss, H., et al., 1995. Blood 85:3378. 2. Sica, G., et al., 2000. Adv. Exp. Med. Biol. 465:355. 3. Alderson, M., et al., 199 |
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