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| Catalog Code: | NB100-77883 |
| Product Name: | B7-H2 Antibody |
| Product Description: | Mouse Monoclonal anti-B7-H2 (2D3), conjugated to Biotin |
| Clone: | 2D3 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Human B7H2-mIg fusion protein |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by activated monocytes/macrophages and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2b, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-CD275 antibody, anti-ICOSL antibody, anti-B7H2 antibody, anti-ICOS-L antibody, anti-B7RP-1 antibody, anti-B7-RP1,a nti-B7RP1 antibody |
| Package Size: | 0.1 mg |
| Conjugate: | Biotin |
| General References: | 1. Wang, S., et al., 2002. J. Biol. Chem. 96:2808. 2. Wong, S.C., et al., 2003. Blood 102:1831. |
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