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| Catalog Code: | NB100-77866 |
| Product Name: | TRAIL Antibody |
| Product Description: | Mouse Monoclonal anti-TRAIL (RIK-2), conjugated to Biotin |
| Clone: | RIK-2 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Human TRAIL-transfected mouse cell line |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | TRAIL is a 30 kD protein known as TNF-related apoptosis inducing ligand, CD253, TNFSF10, or Apo-2L. It can be expressed as a cell surface (30 kD) and soluble ligand (19-20 kD) produced by megakaryocytes and platelets, monocytes, neutrophils, NK cells and activated T cells. This antigen is also expressed on tumor cells and transformed cell lines. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. This antibody is useful for flow cytometric staining and blocking studies. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | anti-Apo-2 ligand antibody, anti-Apo2 ligand antibody, anti-Apo-2L antibody, anti-Apo2L antibody, anti-TNFSF10 antibody, anti-CD253 antibody |
| Package Size: | 0.1 mg |
| Conjugate: | Biotin |
| General References: | 1. Pitti, R.M., et al. 1996. J. Biol. Chem. 271:12687.2. Mariani, S. M., et al. 1998. Eur. J. Immunol. 28:973.3. Dorothee, G., et al. 2002. J. Immunol. 169:809. |
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