| CatalogCode: | | NB100-77719 |
| ProductName: | | CD28 Antibody |
| Product Description: | | Mouse Monoclonal anti-CD28 (JJ319), conjugated to FITC |
| Clone: | | JJ319 |
| Clonality: | | Monoclonal |
| Immunogen: | | Rat CD28-transfected BALB/c mouse A2OJ cell line |
| CrossReactivity: | | Rat. |
| Packaging: | | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | All alpha/ betaTCR+ T cells, most gamma/ deltaTCR+ T cells, NK cell subset |
| Background: | | CD28 is a 44 kD glycoprotein also known as Tp44 or T44. It is a member of the immunoglobulin superfamily and is expressed on thymocytes, alpha/ betaTCR+ T cells, most gamma/ deltaTCR+ T cells, and an NK cell subset. During interaction with CD80 (B7-1) or CD86 (B7-2), CD28 acts as the second signal for T cell stimulation. The JJ319 antibody has been reported to augment in vitro T cell proliferation and enhance IL-2 production. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG1, kappa |
| Host_Name: | | Mouse |
| Buffer: | | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| ListPrice: | | 325 |
| AppSummary: | | FACS |
| SpeciesSummary: | | Rt |
| ALTnames: | | anti-Tp44 antibody,a nti-Tp-44 antibody, anti-T44 antibody, anti-T-44 antibody |
| ProteinTarget: | | CD28 |
| PackageSize: | | 0.5 mg |
| Conjugate: | | FITC |
| GeneralRef: | | 1. Tacke M., et al., 1995. J. Immunol. 154:5121. 2. Mitnancht, R., et al., 1995. Eur. J. Immunol. 25:328. 3. Tacke, M., et al., 1997. Eur. J. Immunol. 27:239. |
| more information: | | company product webpage |