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| Catalog Code: | NB100-77718 |
| Product Name: | CD28 Antibody |
| Product Description: | Mouse Monoclonal anti-CD28 (JJ319) |
| Clone: | JJ319 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Rat CD28-transfected BALB/c mouse A2OJ cell line |
| Cross Reactivity: | Rat. |
| Packaging: | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD28 is a 44 kD glycoprotein also known as Tp44 or T44. It is a member of the immunoglobulin superfamily and is expressed on thymocytes, alpha/ betaTCR+ T cells, most gamma/ deltaTCR+ T cells, and an NK cell subset. During interaction with CD80 (B7-1) or CD86 (B7-2), CD28 acts as the second signal for T cell stimulation. The JJ319 antibody has been reported to augment in vitro T cell proliferation and enhance IL-2 production. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis, immunoprecipitation |
| Species Summary: | Rt |
| Alternate Names: | anti-Tp44 antibody,a nti-Tp-44 antibody, anti-T44 antibody, anti-T-44 antibody |
| Package Size: | 0.5 mg |
| General References: | 1. Tacke M., et al., 1995. J. Immunol. 154:5121. 2. Mitnancht, R., et al., 1995. Eur. J. Immunol. 25:328. 3. Tacke, M., et al., 1997. Eur. J. Immunol. 27:239. |
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