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| Catalog Code: | NB100-77715 |
| Product Name: | CD8b Antibody |
| Product Description: | Mouse Monoclonal anti-CD8b (341) |
| Clone: | 341 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | CD8+ Wistar rat splenic T cell hybridomas |
| Cross Reactivity: | Rat. |
| Packaging: | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. Immunohistochemistry. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD8b antigen is also known as T8, Lyt2, Ly-2, and CD8 beta. It is a member of the immunoglobulin superfamily expressed on most thymocytes, some mature T cell subsets, and macrophages. CD8b forms heterodimers with the CD8 alpha chain (CD8a). CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck). |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis, immunohistochemistry, immunoprecipitation, Western Blot |
| Species Summary: | Rt |
| Alternate Names: | anti-CD8 beta antibody, anti-Lyt3 antibody, anti-Lyt-3 antibody |
| Package Size: | 0.5 mg |
| General References: | 1. Torres-Nagel, N., et al., 1992. Eur. J. Immunol. 22:2841. 2. Kuhnlein, P., et al., 1994 |
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