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| Catalog Code: | NB100-77705 |
| Product Name: | CD86 Antibody |
| Product Description: | Mouse Monoclonal anti-CD86 (24F) |
| Clone: | 24F |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | HTLV-1-transformed Lewis-S1 rat T cell line |
| Cross Reactivity: | Rat. |
| Packaging: | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. Immunohistochemistry-frozen sections. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD86 is an 80 kD member of the immunoglobulin superfamily also known as B70 or B7-2. It is expressed on antigen presenting cells and activated T and B cells. CD86 is a ligand for CD28 and CD152 (CTLA-4). It is one of the accessory molecules that plays an important role in T cell-APC cell costimulatory interactions. The 24F antibody can block the co-stimulatory activity of CD86. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis , immunoprecipitation , Immunohistochemistry-Frozen |
| Species Summary: | Rt |
| Alternate Names: | anti-B7-2 antibody anti-B7 2 antibody, anti-B70 antibody |
| Package Size: | 0.5 mg |
| General References: | 1. Barclay, A.N. et al., 1997. The Leukocyte Antigen FactsBook. Academic Press. 2. Hathcock, K.S., et al., 1993. Science 262:905. 3. Freeman, G.J., et al., 1993. Science 262:907. |
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