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| Catalog Code: | NB100-77688 |
| Product Name: | Flk-1 Antibody |
| Product Description: | Rat Monoclonal anti-Flk-1 (89B3A5) |
| Clone: | 89B3A5 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Rat-1 cells transfected with full-length mouse Flk |
| Cross Reactivity: | Mouse. |
| Packaging: | 0.1 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | The 89B3A5 antibody recognizes mouse Flk-1 also known as vascular endothelial growth factor receptor 2, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF or VEGFC; ligand binding plays a key role in vascular development and vascular permeability. The 89B3A5 antibody has been shown to be useful for flow cytometry. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2a, kappa |
| Host Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Mu |
| Alternate Names: | anti-Vascular endothelial growth factor receptor 2 antibody, anti-VEGFR2 antibody, anti-VEGFR-2 antibody, anti-KDR antibody, anti-protein tyrosine kinase receptor flk-1 antibody, anti-fetal liver kinase-1 antibody |
| Package Size: | 0.1 mg |
| General References: | 1. Patterson, C., et al. 1995. J. Biol. Chem. 270:23111.2. Quinn, T.P., et al., 1993. Proc. Natl. Acad. Sci. USA 90:7533. |
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