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| Catalog Code: | NB100-77627 |
| Product Name: | CD11c Antibody |
| Product Description: | Hamster Monoclonal anti-CD11c (N418), conjugated to Biotin |
| Clone: | N418 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Cross Reactivity: | Mouse. |
| Packaging: | 0.5 mg Immunogen affinity purified Hamster antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for other applications. |
| Background: | CD11c is a 150 kD glycoprotein, also known as alphaX integrin, CR4, or p150. CD11c forms a alphaX beta2 heterodimer with beta2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The alphaX beta2 integrin plays an important role in cell-cell contact by binding its ligands, iC3b, fibrinogen, and CD54. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Hamster |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Mu |
| Alternate Names: | anti-CR4 antibody, anti-p150 antibody, anti-alpha integrin X antibody |
| Package Size: | 0.5 mg |
| Conjugate: | Biotin |
| General References: | 1. Barclay, A., et al., 1997. The Leukocyte Antigen Facts Book, Academic Press. 2. Springer, T.A. 199 |
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