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| Catalog Code: | NB100-77615 |
| Product Name: | I-Ab Antibody |
| Product Description: | Mouse Monoclonal anti-I-Ab (AF6-120.1), conjugated to Biotin |
| Clone: | AF6-120.1 |
| Clonality: | Monoclonal |
| ListPrice: | 315 |
| Immunogen: | C57BL/10J splenocytes |
| Cross Reactivity: | Mouse b haplotype, Cross-reacts with H-2 k and H-2 u haplotypes. Does not react with other haplotypes (e.g., d, f, q, r, s).. |
| Packaging: | 0.5 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one millioncells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | The AF6-120.1 antibody reacts with the I-Ab MHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The AF6-120.1 antibody cross-reacts with H-2k and H-2u haplotypes; this antibody does not cross-react with other haplotypes (d, f, q, r, s). |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2a, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Mu |
| Alternate Names: | anti-MHC class II Ab antibody |
| Package Size: | 0.5 mg |
| Conjugate: | Biotin |
| General References: | 1. Watts, C. 1997. Ann. Rev. Immunol. 15:821. 2. Pamer, E., et al., 1998. Ann. Rev. Immunol. 16:323. |
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