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| Catalog Code: | NB100-77536 |
| Product Name: | PD-1 Antibody |
| Product Description: | Rat Monoclonal anti-PD-1 (RMP1-30) |
| Clone: | RMP1-30 |
| Clonality: | Monoclonal |
| ListPrice: | 315 |
| Immunogen: | Mouse PD-1 transfected BHK cells |
| Cross Reactivity: | Mouse. |
| Packaging: | 0.5 mg Immunogen affinity purified Rat antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2b, kappa |
| Host Name: | Rat |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis, Western Blot |
| Species Summary: | Mu |
| Alternate Names: | anti-Programmed Death-1 antibody, anti-CD279 antibody, anti-PD1 antibody, anti-PD 1 antibody |
| Package Size: | 0.5 mg |
| General References: | 1. Barclay, A., et al., 1997. The Leukocyte Antigen FactsBook, Academic Press. 2. Agata, Y., et al., 1996. Int. Immunol. 8:765. 3. Nishimura, H., et al., 2001. Science 291:319. |
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