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| Catalog Code: | NB100-77492 |
| Product Name: | CD154 Antibody |
| Product Description: | Hamster Monoclonal anti-CD154 (MR1), conjugated to Biotin |
| Clone: | MR1 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Activated mouse Th1 clone D1.6 |
| Cross Reactivity: | Mouse. |
| Packaging: | 0.5 mg Immunogen affinity purified Hamster antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one million cells in 100 microliter volume It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD154 is a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4+ lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation. The MR1 antibody has been reported to inhibit the activation of T and B lymphocytes in vitro and antigen-specific lymphocyte responses in vivo. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Hamster |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Mu |
| Alternate Names: | anti-CD40 Ligand antibody, anti-CD 40 Ligand antibody, anti-CD40L antibody, anti-gp39 antibody, anti-T-BAM antibody, anti-TRAP antibody, anti-Ly62 antibody, anti-Ly-62 antibody, anti-TNSF5 antibody |
| Package Size: | 0.5 mg |
| Conjugate: | Biotin |
| General References: | 1. Barclay, A., et al., 1997. The Leukocyte Antigen FactsBook, Academic Press. 2. Noelle, R.J., et al., 1992. PNAS 89:6550. 3. Bancherou, J., et al., 199 |
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