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| Catalog Code: | NB100-77485 |
| Product Name: | CD137 Antibody |
| Product Description: | Hamster Monoclonal anti-CD137 (17B5), conjugated to Biotin |
| Clone: | 17B5 |
| Clonality: | Monoclonal |
| ListPrice: | 315 |
| Cross Reactivity: | Mouse. |
| Packaging: | 0.5 mg Immunogen affinity purified Hamster antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CDw137 is a 39 kD TNF-receptor superfamily member also known as 4-1BB, TNFRSF9, Ly-63, and ILA (Induced by Lymphocyte Activation). CDw137 is expressed as monomers, dimers, and tetramers on activated T and B cells. Interaction of CDw137 with its ligand, 4-1BBL (CDw137L), is important in T-B cell costimulation. The 17B5 antibody has been reported to block 4-1BBL costimulated T cell proliferation. |
| Storage: | Store at 4C. Do not freeze. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Hamster |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Mu |
| Alternate Names: | anti-4-1BB antibody, anti-TNFRSF9 antibody, anti-Ly63 antibody, anti-Ly-63 antibody, anti-ILA antibody, anti-CDw137 antibody, anti-CD137 antibody |
| Package Size: | 0.5 mg |
| Conjugate: | Biotin |
| General References: | 1. Barclay, A., et al., 1997. The Leukocyte Antigen FactsBook, Academic Press. 2. Alderson, M.R., et al., 1994 |
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