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| Catalog Code: | NB100-77456 |
| Product Name: | CD81 Antibody |
| Product Description: | Hamster Monoclonal anti-CD81 (Eat-2) |
| Clone: | Eat-2 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | CD81+ mouse B lymphoma 38C13 |
| Cross Reactivity: | Mouse, Rat. |
| Packaging: | 0.5 mg Immunogen affinity purified Hamster antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one million cells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells and fibroblasts. CD81 induces B cell adhesion via the VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells. The Eat-2 antibody reacts with mouse and rat CD81. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Hamster |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | flow cytometry / FACS analysis, immunoprecipitation, Western Blot |
| Species Summary: | Mu, Rt |
| Alternate Names: | anti-TAPA-1 antibody, anti-TAPA1 antibody |
| Package Size: | 0.5 mg |
| General References: | 1. Barclay, A.N., et al., 1997. The Leukocyte Antigen FactsBook, Academic Press. 2. Levy, S., et al., 1998. Annu. Rev. Immunol. 16:89. 3. Maeker, H.T., et al., 1997. FASEB J. 11:428. |
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