| CatalogCode: | NB100-774 |
| ProductName: | PGAM1 Antibody |
| Product Description: | Goat Polyclonal anti-PGAM1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide KAMEAVAAQGKAKK representing the C-terminus of the human protein (residues 241-254), according to NP_002620; NP_000281. |
| CrossReactivity: | Cross-reacts with Human. Expected to cross-react with Mouse, Rat and Monkey due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for Western Blot, where a 28kDa band is seen in human liver and brain lysates. Not tested in any other application. Western Blot:Recommended Starting Dilution*:WB: Use at a concentration of 0.5 - 2 ug/ml. *Optimal dilutions/concentrations should be determined by the end user. |
| Control: | Human liver and brain lysates. |
| Background: | PGAM is an enzyme that catalyzes 3 reactions; the isomerization of 2-PGA to 3-PGA with 2,3-DPG as a primer, the synthesis of 2,3-DPG from 1,3-DPG with 3-PGA as a primer and the degradation of 2,3-DPG to 3-PGA. There are two different isoforms of PGAM in mammals, a muscle and brain isoform. PGAM has also been linked to non-spherocytic anemia. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB |
| ALTnames: | anti-PGAM1 antibody, anti-phosphoglycerate mutase 1 (brain) antibody, anti-PGAMA antibody, anti-RP11-452K12.8 antibody, anti-OTTHUMP00000059414 antibody, anti-Phosphoglycerate mutase A antibody, anti-nonmuscle form antibody, anti-PGAM2 antibody, anti-phosphoglycerate mutase 2 (muscle) antibody, anti-MGC88743 antibody, anti-PGAMM antibody, anti-Phosphoglycerate mutase antibody, anti-muscle form antibody, anti-PGAM3 antibody, anti-PGAM4 antibody, anti-phosphoglycerate mutase family member 4 antibody, anti-PGAM-B antibody, anti-dJ1000K24.1 antibody, anti-phosphoglycerate mutase family 3 antibody, anti-phosphoglycerate mutase family 4 antibody, anti-phosphoglycerate mutase processed protein antibody |
| ProteinTarget: | PGAM1 antibody |
| PackageSize: | 0.1 mg |
| GeneralRef: | General / background references:Sakoda S et al. Isolation of a cDNA encoding the B isozyme of human phosphoglycerate mutase (PGAM) and characterization of the PGAM gene family. J Biol Chem 263:16899-905 (1988). |
| NotesMain: | This antibody is expected to recognize the products of 3 highly similar genes. |
| Gene_Id: | 5223 |
| Omim_ID: | NB100-66284 |