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| Catalog Code: | NB100-77335 |
| Product Name: | GOT1 Antibody |
| Product Description: | Goat Polyclonal anti-GOT1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 2805 (human); 14718 (mouse); |
| Gene Symbol: | GOT1 |
| Reference Sequence: | NP_002070.1 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide, C-TADFREDPDPRKVN, representing the internal region of the sequence according to NP_002070.1 |
| Epitope: | TADFREDPDPRKVN |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 40kDa band observed in Human Liver lysates (calculated MW of 46.2kDa according to NP_002070.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Berk et al, Proc Natl Acad Sci U S A. 1990 May;87(9):3484-8; PMID: 2185471). Recommended concentration: 0.5-1.5ug/ml. |
| Localization: | Cytoplasmic and Mitochondrial |
| Background: | Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Application Summary: | ELISA 1:16000, Western Blot 0.5-1.5ug/ml |
| Species Summary: | Hu |
| Alternate Names: | anti-glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) antibody, anti-GIG18 antibody, anti-aspartate aminotransferase 1 antibody, anti-growth-inhibiting protein 18 antibody, anti-GOT1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% sodium azide |
| Homology: | Human, Mouse |
| General References: | Teichberg VI.From the liver to the brain across the blood-brain barrier.Proc Natl Acad Sci U S A. 2007 May 1;104(18):7315-6. Epub 2007 Apr 26. Noabstract available. |
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