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| Catalog Code: | NB100-77327 |
| Product Name: | CAD Antibody |
| Product Description: | Rabbit Polyclonal anti-CAD |
| Clonality: | Polyclonal |
| ListPrice: | 375 |
| Gene ID: | 790 |
| Reference Sequence: | NP_004332.2 |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 1650 and 1700 of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase using the numbering given in entry NP_004332.2 (GeneID 790). |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry on paraffin sections. Epitope exposure with citrate bufferexposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. |
| Background: | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| Application Summary: | Immunohistochemistry-Paraffin 1:100-1:500 |
| Species Summary: | Hu |
| Alternate Names: | anti-CAD antibody, anti-carbamoyl-phosphate synthetase 2 antibody, anti-aspartate transcarbamylase antibody, anti-and dihydroorotase antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.09% sodium azide |
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