| CatalogCode: | NB100-77326 |
| ProductName: | PARP1 Antibody |
| Product Description: | Rabbit Polyclonal anti-PARP1 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 50 and 100 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142). |
| CrossReactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry on paraffin sections. Epitope exposure with citrate bufferexposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. |
| Background: | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 375 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | anti-PARP antibody, anti-PARP1 antibody, anti-PARP-1 antibody, anti-poly (ADP-ribose) polymerase family antibody, anti-member 1 antibody, anti- ADPRT antibody, anti-ADPRT1 antibody, anti-ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) antibody, anti-PPOL antibody, anti-poly(ADP-ribose) polymerase antibody |
| ProteinTarget: | PARP1 |
| PackageSize: | 0.1 ml |
| Gene_Id: | 142 |
| Ref_Sqnce: | NP_001609.1 |