| Catalog Code: | NB100-755 |
| Product Type: | Primary Antibody |
| Product Name: | Pds5B Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 23047 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-Pds5B |
| Cross Reactivity: | Human and mouse. Other species have not been tested. Reactivity with X. laevis Pds5B is unlikely owing to divergence of sequence between this ortholog and human Pds5B at the site to which the epitope maps. |
| Species Summary: | Hu, Mu |
| Background: | Pds5B is a cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. It plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis |
| Alternate Names: | anti-Precocious Dissociation of Sisters-5B antibody, anti-Aprin antibody, anti-Androgen-Induced Proliferation Inhibitor antibody, anti-AS3 antibody, anti-Androgen-Induced Shutoff 3 antibody, anti-Spo76 antibody, anti-BimD antibody |
| Immunogen: | A synthetic peptide mapping to a region between residue 1400 and the C-terminus (residue 1447) of human Precocious Dissociation of Sisters-5B using the numbering given in entry CAB69911.1 (GeneID 23047). |
| Localization: | Nuclear |
| Packaging: | 0.1 ml of affinity purified rabbit sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1% sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 0.2 mg/ml |
| Uses: | NB 100-755 may be used for immunoprecipitation and Western Blot. Other applications have not been tested. Suggested working dilutions: * Western Blot: 1:2,000 - 1:10,000. Immunoprecipitation: 2 to 5 ug/mg lysate. *The investigator should determine the |
| Application Summary: | IP, WB |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |