| CatalogCode: | | NB100-68232 |
| ProductName: | | SART1 Antibody |
| Product Description: | | Rabbit Polyclonal anti-SART1 |
| Clonality: | | Polyclonal |
| Immunogen: | | The epitope recognized by this antibody maps to a region between residue 675 and 725 of human squamous cell carcinoma antigen recognized by T cells using the numbering given in entry NP_005137.1 (GeneID 9092). |
| CrossReactivity: | | Human. |
| Packaging: | | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | | This antibody is useful for immunoprecipitation. It is not recommended for western blot. |
| Background: | | This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | Tris-citrate/phosphate buffer, pH 7 to 8 |
| ListPrice: | | 325 |
| AppSummary: | | IP |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-SART1 antibody, anti-SART-1 antibody, anti-squamous cell carcinoma antigen recognized by T cells antibody, anti-Ara1 antibody, anti-HOMS1 antibody, anti-SART1259 antibody, anti-Snu66 antibody |
| ProteinTarget: | | SART1 |
| PackageSize: | | 0.1 mg |
| Gene_Id: | | 9092 |
| Ref_Sqnce: | | NP_005137.1 |
| more information: | | company product webpage |