| CatalogCode: | NB100-68212 |
| ProductName: | AKAP12/Gravin Antibody |
| Product Description: | Rabbit Polyclonal anti-AKAP12/Gravin |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 1731 and 1781 of human A kinase (PRKA) anchor protein (gravin) 12 using the numbering given in entry AAC51366.1 (GeneID 9590). |
| CrossReactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for western blot and immunoprecipitation. |
| Background: | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 325 |
| AppSummary: | WB, IP |
| SpeciesSummary: | Hu |
| ALTnames: | anti-AKAP12 antibody, anti-AKAP-12 antibody, anti-A kinase (PRKA) anchor protein 12 antibody, anti-Gravin antibody, anti-myasthenia gravis autoantigen gravin antibody, anti-AKAP250 antibody, anti-A kinase (PRKA) anchor protein 250kDa antibody |
| ProteinTarget: | AKAP12/Gravin |
| PackageSize: | 0.02 mg |
| Gene_Id: | 9590 |
| Ref_Sqnce: | AAC51366.1 |