| CatalogCode: | NB100-68148 |
| ProductType: | Primary Antibody |
| ProductName: | IDE Antibody |
| ListPrice: | 295 |
| Clonality: | Polyclonal |
| Gene_Id: | 3416 |
| Host: | Goat |
| Isotype: | IgG |
| ProductDescription: | Goat Polyclonal anti-Insulysin / Insulinase |
| CrossReactivity: | Human. Other species not tested. Expected based upon sequence homology: Dog |
| SpeciesSummary: | Hu |
| Background: | This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insuli |
| ALTnames: | anti-insulin-degrading enzyme antibody, anti-FLJ35968 antibody, anti-INSULYSIN antibody, anti-insulinase antibody, anti-insulysin antibody |
| Immunogen: | Synthetic peptide, C-QQYNFDRDNTE, representing the internal region of the sequence according to NP_004960.1 |
| Epitope: | QQYNFDRDNTE |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Preservative: | 0.02% sodium azide |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| PackageSize: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 110-120kDa band observed in Human lysates of cell line K562 (calculated MW of 118kDa according to NP_004960.1). Recommended concentration: 0.1-0.3ug/ml. |
| AppSummary: | ELISA, WB |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| GeneralRef: | Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM.Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.Neurobiol Aging. 2007 Jun;28(6):824-30. Epub 2006 |