| CatalogCode: | NB100-66481 |
| ProductName: | SYNAPSIN Antibody |
| Product Description: | Rabbit Polyclonal anti-SYNAPSIN |
| Clonality: | Polyclonal |
| Immunogen: | Native, (a+b) from brain |
| Specificity: | This antibody recognises both Synapsin 1a (86 kD)and Synapsin 1b (80 kD). As synapsin is unstable Western blots may show bands at 45 and 60 kD due to proteolytic fragmentation. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein A purified Rabbit antisera. |
| Uses: | This antibody is useful for Western Blot, ELISA |
| Localization: | Cell junction; synapse |
| Background: | Synapsin I is a member of the synapsin family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations of the Synapsin I gene may be associated with X linked disorders with primary neuronal degeneration such as Rett syndrome. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Brain protein 4.1 antibody, anti-SYN 1 antibody, anti-SYN 1a antibody, anti-SYN 1b antibody, anti-SYN I antibody, anti-SYN1 antibody, anti-SYN1a antibody, anti-SYN1b antibody, anti-Synapsin 1 antibody, anti-Synapsin1 antibody, anti-SynapsinI antibody, anti-SYNI antibody |
| ProteinTarget: | SYNAPSIN |
| PackageSize: | 0.1 mg |
| NotesMain: | Immunohistology: Has not been investigated, but purified synapsin is a highly unstable protein. |