| CatalogCode: | NB100-66420 |
| ProductName: | GAD 65 Antibody |
| Product Description: | Rabbit Polyclonal anti-GAD 65 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to the amino acids 8 - 20 of the native molecule conjugated to Keyhole limpet Haemocyanin. |
| Epitope: | F-W-S-F-G-S-E-D-G-S-G-D-S-{C} |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 1 ml of Ammonium Sulphate fractionation Purified IgG |
| Uses: | This antibody is useful for Western Blot, ELISA |
| Localization: | Cytoplasmic |
| Background: | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | WB, ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-65 kDa glutamic acid decarboxylase antibody, anti-DCE 2 antibody, anti-DCE2 antibody, anti-GAD 2 antibody, anti-GAD 65 antibody, anti-GAD-2 antibody, anti-GAD-65 antibody, anti-GAD2 antibody, anti-Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) antibody, anti-Glutamate Decarboxylase 2 antibody, anti-Glutamate Decarboxylase 65 antibody, anti-Glutamate decarboxylase 65 kDa isoform antibody, anti-Glutamic Acid Decarboxylase 2 antibody, anti-Glutamic Acid Decarboxylase 65 antibody |
| ProteinTarget: | GAD 65 |
| PackageSize: | 1 ml |