| Catalog Code: | NB100-659 |
| Product Type: | Primary Antibody |
| Product Name: | DNA-PKcs Antibody |
| List Price: | 300 |
| Clonality: | Polyclonal |
| Gene ID: | 5591 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-DNA-PKcs |
| Cross Reactivity: | Human. Not tested in other species. Reactivity with infraprimates is unlikely owing to divergence of sequence between these orthologs and human DNA-PKcs at the site to which the epitope maps. |
| Species Summary: | Hu |
| Background: | DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine |
| Alternate Names: | anti-DNAPK antibody, anti-DNAPK1 antibody, anti-DNA-PKcs antibody, anti-DNA-Dependent Protein Kinase antibody, anti-catalytic subunit antibody, anti-PRKDC antibody, anti-Protein Kinase antibody, anti-DNA-activated antibody, anti-catalytic subunit antibody |
| Immunogen: | The epitope maps to a region between residues 2100 and 2150 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591). |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-buffered saline containing 0.1% BSA & 0.09% Sodium Azide |
| Packaging: | 0.1 ml affinity purified antisera |
| Package Size: | 0.1ml |
| Concentration: | 0.2 mg/ml |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:1,000 to 1:10,000. Immunoprecipitation: Not recommended. Use N |
| Application Summary: | WB |