| CatalogCode: | NB100-65856 |
| ProductName: | CD106 Antibody |
| Product Description: | Mouse Monoclonal anti-CD106 (STA) |
| Clone: | STA |
| Clonality: | Monoclonal |
| Immunogen: | Cells of the DS6 T-cell line |
| Specificity: | NB100-65856 recognises human CD106, a 110kD cell surface protein predominantly expressed on activated vascular endothelium. CD106, also known as vascular cell adhesion molecule 1 (VCAM-1), is also expressed by several non-endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells.CD106 binds the integrins alpha4 beta1 and alpha4 beta7 and mediates leucocyte-endothelial cell adhesion. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for immunoprecipitation, flow cytometry / FACS analysis |
| Localization: | Plasma membrane, Type I membrane protein. |
| Background: | VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline pH7.4 |
| ListPrice: | 295 |
| AppSummary: | FACS, IP |
| SpeciesSummary: | Hu |
| ALTnames: | anti-VCAM1 antibody, anti-CD 106 antibody, anti-CD106 antibody, anti-CD106 Antigen antibody, anti-DKFZp779G2333 antibody, anti-INCAM 100 antibody, anti-L1CAM antibody, anti-MGC99561 antibody, anti-Vascular Cell Adhesion Molecule 1 antibody, anti-Vascular cell adhesion protein 1 antibody, anti-VCAM 1 antibody |
| ProteinTarget: | CD106 |
| PackageSize: | 0.2 mg |